Skip to content
  • Happy Health
  • Happy Mindset
  • Animal Wonders
  • About Us
    • Team
  • Subscribe
Menu
  • Happy Health
  • Happy Mindset
  • Animal Wonders
  • About Us
    • Team
  • Subscribe
Happy News

Major Breakthrough Against The World’s Deadliest Infectious Disease

MIT biological engineers have identified several promising vaccine targets that could finally provide better protection against tuberculosis, the world’s deadliest infectious disease that kills more than 1 million people every year. The only current vaccine for TB, called BCG, was developed over 100 years ago from a weakened cow bacterium and poorly protects adults against pulmonary tuberculosis. Researchers faced a daunting challenge in screening more than 4,000 proteins produced by the Mycobacterium tuberculosis bacteria to find which ones might trigger a strong immune response.

The team infected human cells with the bacteria, then used mass spectrometry to identify which bacterial peptides appeared most often on cell surfaces where they could activate T cells. Out of thousands of proteins, they narrowed the field to 27 TB peptides from 13 proteins, and further testing showed that 24 of these successfully triggered T cell responses in people previously infected with TB. The researchers created experimental mRNA vaccines using proteins from the type 7 secretion system, finding that vaccines targeting cell lysosomes were 1,000 times more effective at inducing immune response than others. While the team currently has a mix of eight proteins they believe could protect most people against TB, they continue testing combinations with blood samples from around the world, with human trials likely still several years away but offering genuine hope for conquering this ancient killer.

PrevPreviousWoman Loses Her Sight And Discovers Something More Valuable
NextThe Truth Behind These Famous Weekend Cinnamon RollsNext

Recent Articles

Happy News

Woman Loses Her Sight And Discovers Something More Valuable

November 13, 2025

When writer Merilyn Simonds turned 70, she realized she didn’t have a roadmap for the years ahead and thought her 100 year old friend Beth Robinson might have some wisdom to share. The two women from Kingston, Ontario have been friends for so long they don’t remember when they met,

Read More
Happy News

Scientists Discover DNA Can Do Something Nobody Ever Imagined

November 13, 2025

Scientists at the National University of Singapore have discovered that DNA can do far more than just carry genetic information. Researchers found that specific regions of DNA called phosphates act like tiny hands that guide chemical reactions to create the correct mirror image form of drug molecules, solving a major

Read More
Happy News

The Seven Foot Nine Canadian Who Just Made Basketball History

November 13, 2025

Olivier Rioux from Terrebonne, Quebec has officially become the tallest player in college basketball history after stepping onto the court for the University of Florida. The 19 year old stands at an incredible seven feet nine inches tall, towering over current NBA stars like Victor Wembanyama and even legendary giants

Read More
« Previous Next »
  • Privacy Notice
  • Accessibility Notice
  • Do Not Sell or Share My Personal Information
  • Unsubscribe
  • Terms and Conditions
  • Privacy Policy
  • Privacy Notice
  • Accessibility Notice
  • Do Not Sell or Share My Personal Information
  • Unsubscribe
  • Terms and Conditions
  • Privacy Policy
Copyright © 2025 HappyNews.