Skip to content
  • Happy Health
  • Happy Mindset
  • Animal Wonders
  • About Us
    • Team
  • Subscribe
Menu
  • Happy Health
  • Happy Mindset
  • Animal Wonders
  • About Us
    • Team
  • Subscribe
Happy News

This Drug Enters Cancer Cells 12.5x Faster With NO Side Effects

Researchers at Northwestern University have completely reimagined a classic chemotherapy drug using nanotechnology, transforming a weak, poorly soluble compound into a precision cancer therapy that is up to 20,000 times more effective at destroying cancer cells. The scientists created the drug entirely from scratch as a spherical nucleic acid, a nanoscale structure that incorporates the medication into DNA strands surrounding tiny spheres, which dramatically improves how the body absorbs and uses it. Traditional chemotherapy drug 5 fluorouracil dissolves so poorly that less than one percent of it works in many biological fluids, causing it to clump in solid form that the body cannot absorb efficiently while also attacking healthy tissue and causing terrible side effects like nausea, fatigue, and even heart failure. When tested in a small animal model of acute myeloid leukemia, an aggressive and hard to treat blood cancer, the redesigned version entered leukemia cells 12.5 times more efficiently, destroyed them up to 20,000 times more effectively, and slowed cancer progression by a factor of 59.

The breakthrough happened because the structural redesign changed how the drug interacted with cancer cells, allowing myeloid cells to easily recognize and absorb the spherical nucleic acid form before enzymes broke down the DNA shell to release drug molecules that killed the cancer from within. In mouse experiments, the therapy eliminated leukemia cells to near completion in the blood and spleen, significantly extended survival, and left healthy tissues completely unharmed because it selectively targeted only the cancer cells. Today’s chemotherapeutics kill everything they encounter including healthy cells, but this structural nanomedicine preferentially seeks out myeloid cells and delivers a higher, more focused dose exactly where it’s needed instead of overwhelming the whole body. With seven spherical nucleic acid based therapies already in clinical trials, this approach could pave the way for advanced vaccines and new treatments for cancer, infectious diseases, neurodegenerative disorders, and autoimmune conditions.

PrevPreviousDiagnosed At 11 And He’s CHANGING Cancer Research

Recent Articles

HAppy News

Woman Pulls Stranger From River Then Watches Him Say I Do

November 3, 2025

Rachelle Ruffing and her family were paddleboarding on Idaho’s Snake River in 2020, trying to ease the pain of losing their beloved dog the day before, when she spotted an empty kayak pop through Pillar Falls and start to sink. What she didn’t see in that terrifying moment was Brendon

Read More
Happy News

12 Year Old Endures Taunts To Change Another Child’s Life

November 3, 2025

Twelve year old Jack from Cardiff endured two years of playground taunts and name calling, earning the nickname Goldilocks from classmates who mocked his long blond curly hair, but he refused to cut it because he knew his growing locks were going to change a child’s life. The determined youngster

Read More
Happy News

NHS Just Made This Drug FREE At Every Pharmacy

November 3, 2025

The NHS just made history by announcing that emergency contraception will be available completely free at pharmacies across England, removing cost barriers that have prevented women from accessing this time sensitive medication. Previously, the morning after pill could cost up to 30 pounds at pharmacies, forcing many women to wait

Read More
« Previous Next »
  • Privacy Notice
  • Accessibility Notice
  • Do Not Sell or Share My Personal Information
  • Unsubscribe
  • Terms and Conditions
  • Privacy Policy
  • Privacy Notice
  • Accessibility Notice
  • Do Not Sell or Share My Personal Information
  • Unsubscribe
  • Terms and Conditions
  • Privacy Policy
Copyright © 2025 HappyNews.