Skip to content
  • Happy Health
  • Happy Mindset
  • Animal Wonders
  • About Us
    • Team
  • Subscribe
Menu
  • Happy Health
  • Happy Mindset
  • Animal Wonders
  • About Us
    • Team
  • Subscribe
Happy News

Replacing Opioids With A Cannabis Compound That Has No High And No Addiction

Scientists are closing in on something the medical world has been searching for for decades: a way to treat chronic pain as effectively as opioids, without the addiction, overdose risk, or mind-altering effects that make opioids so dangerous. Two separate research teams have recently made significant progress toward that goal using compounds derived from the cannabis plant, neither of which contains THC, the psychoactive ingredient responsible for a high. Researchers at the University of Arizona found that terpenes, naturally occurring aromatic compounds found in cannabis, produced significant reductions in chronic pain in preclinical models of both fibromyalgia and post-surgical pain, and did so more effectively than opioids in the conditions tested. The findings were the first to specifically examine terpenes in those two pain contexts, and the lead researcher called them a potentially viable treatment for fibromyalgia, a condition that currently has few good options and affects millions of people.

In a separate line of research, scientists at Washington University School of Medicine and Stanford University designed a custom synthetic compound modeled on a natural cannabis molecule, engineered so that it activates pain-reducing receptors throughout the body but is physically unable to cross into the brain. That design is what makes it so promising: by staying outside the brain, the compound bypasses the reward pathways that make opioids addictive and eliminates the psychoactive effects entirely, while still providing meaningful pain relief in animal models with almost no tolerance buildup over time. The researchers said designing a molecule that relieves pain with minimal side effects is one of the hardest challenges in pharmacology, and this one clears multiple hurdles at once. Neither approach has yet entered human clinical trials, but scientists in both teams said the path forward is clearer than it has ever been.

Source: https://scitechdaily.com/researchers-have-discovered-a-thc-free-cannabis-compound-that-may-replace-opioids/

PrevPreviousThe Worlds Oldest Doctor Ever Worked Until He Was 103 And Guinness Made It Official
NextHappy National Arbor Day! The 154-Year-Old Holiday That Asks You To Plant Just One TreeNext

Recent Articles

Happy News

Scientists May Have Finally “Seen” Dark Matter

May 9, 2026

For nearly a century, dark matter has been one of the greatest mysteries in all of science. We know it exists as it makes up an estimated 85% of the universe’s total mass and acts as invisible gravitational scaffolding holding galaxies together, but no one has ever directly observed it.

Read More
Happy News

Coral Reefs Are Hiding An Almost Entirely Unstudied Universe Of Potential Medicine

May 9, 2026

Scientists at the University of Galway and an international consortium have discovered that coral reefs contain an almost entirely unstudied universe of microbial life, publishing a study in Nature that reconstructed the genomes of 645 microbial species from 99 coral reefs across 32 Pacific islands, with more than 99 percent

Read More
Happy News

A Rare Superbloom Is Turning Part Of Redwood National Park Purple And There Are Only Weeks To See It

May 9, 2026

Something extraordinary and fleeting is happening right now in Northern California, where the Bald Hills grasslands above the redwood canopy in Redwood National Park have erupted into a rare lupine superbloom, turning a stretch of elevated landscape off a remote road near Orick into a sweeping sea of purple, blue,

Read More
« Previous Next »
  • Privacy Notice
  • Accessibility Notice
  • Do Not Sell or Share My Personal Information
  • Unsubscribe
  • Terms and Conditions
  • Privacy Policy
  • Privacy Notice
  • Accessibility Notice
  • Do Not Sell or Share My Personal Information
  • Unsubscribe
  • Terms and Conditions
  • Privacy Policy
Copyright © 2026 HappyNews.