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The Largest Measles Outbreak The US Has Seen In 35 Years Has Ended

South Carolina has officially declared an end to the largest measles outbreak the United States has seen in more than 35 years, with state health officials announcing this week that 42 days have passed without a single new confirmed case, the threshold required to declare an outbreak over. The outbreak, which was centered in Spartanburg County in the state’s Upstate region and began in late September 2025, resulted in 997 confirmed cases over roughly six months, at least 21 hospitalizations, and affected 33 schools, with 874 students asked to quarantine at various points during its peak. More than 97 percent of those infected had not been fully vaccinated against measles, a pattern consistent with outbreaks across the country and a stark reminder of why the MMR vaccine exists. Public health officials called ending it a monumental effort, crediting healthcare workers, communities willing to stay home when asked, and a significant uptick in vaccination rates during the outbreak.

MMR vaccination doses in Spartanburg County increased by 94 percent during the outbreak period compared to the same time the year before, and rose 82 percent across the broader Upstate region, a real-time demonstration of what public awareness can accomplish when people see the consequences of a preventable disease up close. Pediatricians across the region reported previously hesitant families returning to request the vaccine after hearing from neighbors and relatives how serious the illness had been. The good news comes with an honest caveat: more than 20 other measles outbreaks are currently active across the United States, and the country is on track to surpass last year’s record total. But South Carolina’s experience is a powerful proof of concept that outbreaks can be stopped, and that vaccination, community cooperation, and a determined public health response can turn even the worst situation around.

Source: https://edition.cnn.com/2026/04/27/health/south-carolina-measles-outbreak-over

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